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Nausea (28%), diarrhea (23%), constipation (17%), and vomiting (12%) at the 12mg dose are the most commonly reported

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(3) The researchers compared younger and older cells and reported that, apparently, the total amount of FOXO4 protein did not clearly change, but its location did

published dosage figures refer to experimental animal/in-vitro studies, not human protocols

However, no controlled human studies define optimal duration, maintenance dosing, or long-term exposure safety